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3M™ Emphaze™ AEX Series Hybrid Purifier

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3M™ Emphaze™ AEX Series Hybrid Purifier

Over het product

3M™ Emphaze AEX Hybrid Purifier is our single-use sterilisable and sanitisable. The all-synthetic purification media that contains a Q-functional anion exchange media and a fine particle and bioburden reduction membrane.

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Productdetails

Remove impurities in biopharmaceutical process streams such as DNA, host cell proteins (HCP) and viruses with our all-synthetic, single use 3M™ Emphaze AEX Hybrid Purifier. The composite purification media is comprised of three primary components: anion exchange nonwoven, microporous membrane, and membrane support. The anion exchange media is composed of four layers of polypropylene nonwoven with a covalently attached quaternary ammonium functional polymer. The bioburden reduction membrane is a highly asymmetric polyamide membrane which has nine zones of decreasing pore size, spanning approximately a 20 X range, and terminating with a 0.2 μm rated qualifying layer. This is followed by a polypropylene nonwoven used as a support layer in the capsule. Capsules There are two primary capsule configurations for the Emphaze AEX Hybrid Purifier, Laboratory and Scale-up capsules: - The Laboratory capsule (BV8) has an 8ml bed volume - The Scale-up capsules are constructed from a lenticular media cell design having bed volumes of 120 mls and 360 mls (BV 120 and BV 360 respectively) - The Production capsules are scaled to meet your manufacturing requirements and utilise manifolds in a holder for ease of use A full support package is available for 3M Emphaze AEX Hybrid Purifiers. This package includes Installation and Operation Guides, a Certificate of Quality and a Regulatory Support File.
  • Reduces turbidity, HCP, DNA and bioburden.
  • Excellent throughput and mAb recovery.
  • Enhanced capture column performance and protection.
  • Substantial turbidity, DNA, HCP and bioburden reduction.
  • Reduced surface area requirement of the downstream sterilizing grade membrane.
  • May offer differentiated protection of the protein A column for enhanced contaminant clearance performance.
  • All product components comply with United States Pharmacopeia (USP) Class VI 70°C Biological Reactivity Tests, in vivo.

Voorgestelde toepassingen

  • Use for the clarification of mammalian cell cultures and to optimise downstream processes for monoclonal antibodies (mAbs)

Productspecificaties

Industries
Industries

Biofarmaceutische productie

Totale hoogte (imperiaal)
Totale hoogte (imperiaal)

4.06 in, 2.32 in, 5.98 in, 2.24 in, 1.89 in, 1.77 in, 3.46 in

OverallDiameterImperial
OverallDiameterImperial

1.69 in

Totale diameter (metrisch)
Totale diameter (metrisch)

21.6 cm, 4.3 cm, 45.2 cm, 7.7 cm

categoryName
categoryName

Chromatografiefilters

Debiet (metrisch)
Debiet (metrisch)

100 ml/min, 1.4 ml/min, 4700 ml/min, 300 ml/min, 680 ml/min, 0.4 ml/min, 8 ml/min

OverallHeightImperial
OverallHeightImperial

7.99 in

Debiet
Debiet

0.022 gal/min, 1.034 gal/min, 0.011 gal/min, 0.066 gal/min, 0.15 gal/min, 0 gal/min, 0.002 gal/min

OverallHeightMetric
OverallHeightMetric

10.3 cm, 4.8 cm, 8.8 cm

Merk
Merk

Emphaze™

FlowRateImperial
FlowRateImperial

0 gal/min, 0.002 gal/min

NetWeightMetric
NetWeightMetric

71 g

ProductSeries
ProductSeries

AEX

Productserie
Productserie

AEX

Trademark2
Trademark2

Emphaze™

Filtertype
Filtertype

Eenmalig gebruik

Eindaanpassing
Eindaanpassing

3/4 in Sanitary Connectors, 1 1/2 in Sanitary Connectors, Luer Loc

Categorienaam
Categorienaam

Chromatografiefilters

FlowRateMetric
FlowRateMetric

50 ml/min, 8 ml/min

Toepassing
Toepassing

Oogsten en klaring

MicronRating
MicronRating

0.2 μm

Micronage
Micronage

0.2 μm

OverallDiameterMetric
OverallDiameterMetric

45.2 cm, 21.6 cm

Totale hoogte (metrisch)
Totale hoogte (metrisch)

10.3 cm, 5.9 cm, 20.3 cm, 15.2 cm, 5.7 cm, 4.5 cm

EndModification
EndModification

Luer Loc, 3/4 in Sanitary Connectors

Sectoren
Sectoren

Biofarmaceutische productie

FilterType
FilterType

Eenmalig gebruik

Totale diameter (Brits)
Totale diameter (Brits)

8.5 in, 1.69 in, 17.8 in, 3.03 in

Filtertechnologie
Filtertechnologie

Anion exchange-chromatografie

FilterTechnology
FilterTechnology

Anion exchange-chromatografie

Nettogewicht (metrisch)
Nettogewicht (metrisch)

1.1 kg, 14.5 g, 9.5 kg, 1.6 kg, 3.4 kg, 9 g, 77 g

Application
Application

Oogsten en klaring

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